A Developmental Switch in Microglial HDAC Function
The epigenetic mechanisms controlling microglia functions are largely unknown. In this issue of Immunity, Datta et al. (2018) uncover surprising and distinct effects of deleting the epigenetic regulators HDAC1 and HDAC2 during microglial development versus during the course of neurodegeneration.
| Main Authors: | , , |
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| Format: | Article |
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Elsevier BV
2019
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| Online Access: | https://hdl.handle.net/1721.1/122954 |
| _version_ | 1826213364587560960 |
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| author | Mathys, Hansruedi Penney, Jay Tsai, Li-Huei |
| author2 | Picower Institute for Learning and Memory |
| author_facet | Picower Institute for Learning and Memory Mathys, Hansruedi Penney, Jay Tsai, Li-Huei |
| author_sort | Mathys, Hansruedi |
| collection | MIT |
| description | The epigenetic mechanisms controlling microglia functions are largely unknown. In this issue of Immunity, Datta et al. (2018) uncover surprising and distinct effects of deleting the epigenetic regulators HDAC1 and HDAC2 during microglial development versus during the course of neurodegeneration. |
| first_indexed | 2024-09-23T15:47:55Z |
| format | Article |
| id | mit-1721.1/122954 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T15:47:55Z |
| publishDate | 2019 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1229542022-10-02T04:10:18Z A Developmental Switch in Microglial HDAC Function Mathys, Hansruedi Penney, Jay Tsai, Li-Huei Picower Institute for Learning and Memory Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences The epigenetic mechanisms controlling microglia functions are largely unknown. In this issue of Immunity, Datta et al. (2018) uncover surprising and distinct effects of deleting the epigenetic regulators HDAC1 and HDAC2 during microglial development versus during the course of neurodegeneration. 2019-11-15T18:15:14Z 2019-11-15T18:15:14Z 2018-03 Article http://purl.org/eprint/type/JournalArticle 1074-7613 https://hdl.handle.net/1721.1/122954 Mathys, Hansruedi et al. "A Developmental Switch in Microglial HDAC Function." Immunity 48, 3 (March 2018): 476-478 © 2018 Elsevier Inc http://dx.doi.org/10.1016/j.immuni.2018.03.010 Immunity Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/vnd.openxmlformats-officedocument.wordprocessingml.document application/pdf Elsevier BV Prof. Tsai via Courtney Crummett |
| spellingShingle | Mathys, Hansruedi Penney, Jay Tsai, Li-Huei A Developmental Switch in Microglial HDAC Function |
| title | A Developmental Switch in Microglial HDAC Function |
| title_full | A Developmental Switch in Microglial HDAC Function |
| title_fullStr | A Developmental Switch in Microglial HDAC Function |
| title_full_unstemmed | A Developmental Switch in Microglial HDAC Function |
| title_short | A Developmental Switch in Microglial HDAC Function |
| title_sort | developmental switch in microglial hdac function |
| url | https://hdl.handle.net/1721.1/122954 |
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