Antigen structure affects cellular routing through DC-SIGN

Dendritic cell (DC) lectins mediate the recognition, uptake, and processing of antigens, but they can also be coopted by pathogens for infection. These distinct activities depend upon the routing of antigens within the cell. Antigens directed to endosomal compartments are degraded, and the peptides...

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Bibliographic Details
Main Authors: Jarvis, Cassie M., Zwick, Daniel B., Grim, Joseph C., Alam, Mohammad Murshid, Prost, Lynne R., Gardiner, Jaye C., Park, Soyeong, Zimdars, Laraine L., Sherer, Nathan M., Kiessling, Laura L
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: National Academy of Sciences 2020
Online Access:https://hdl.handle.net/1721.1/123339