Antigen structure affects cellular routing through DC-SIGN
Dendritic cell (DC) lectins mediate the recognition, uptake, and processing of antigens, but they can also be coopted by pathogens for infection. These distinct activities depend upon the routing of antigens within the cell. Antigens directed to endosomal compartments are degraded, and the peptides...
Main Authors: | , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences
2020
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Online Access: | https://hdl.handle.net/1721.1/123339 |