Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes

There is a critical need for the development of safe and efficient delivery technologies for CRISPR/Cas9 to advance translation of genome editing to the clinic. Non-viral methods that are simple, efficient, and completely based on biologically-derived materials could offer such potential. Here we...

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Bibliographic Details
Main Authors: Jain, Piyush Kumar, Lo, Justin H., Rananaware, Santosh, Downing, Marco, Panda, Apekshya, Tai, Michelle, Raghavan, Srivatsan, Fleming, Heather, Bhatia, Sangeeta N
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC) 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/123502