Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes

There is a critical need for the development of safe and efficient delivery technologies for CRISPR/Cas9 to advance translation of genome editing to the clinic. Non-viral methods that are simple, efficient, and completely based on biologically-derived materials could offer such potential. Here we...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Jain, Piyush Kumar, Lo, Justin H., Rananaware, Santosh, Downing, Marco, Panda, Apekshya, Tai, Michelle, Raghavan, Srivatsan, Fleming, Heather, Bhatia, Sangeeta N
Weitere Verfasser: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Artikel
Sprache:English
Veröffentlicht: Royal Society of Chemistry (RSC) 2020
Schlagworte:
Online Zugang:https://hdl.handle.net/1721.1/123502