Collagen Prolyl Hydroxylases Are Bifunctional Growth Regulators in Melanoma

Collagen Prolyl Hydroxylases Are Bifunctional Growth Regulators in Melanoma

Appropriate post-translational processing of collagen requires prolyl hydroxylation, catalyzed by collagen prolyl 3-hydroxylase and collagen prolyl 4-hydroxylase, and is essential for normal cell function. Here we have investigated the expression, transcriptional regulation, and function of the coll...

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Bibliographic Details
Main Authors: Atkinson, Aithne, Renziehausen, Alexander, Wang, Hexiao, Lo Nigro, Cristiana, Lattanzio, Laura, Merlano, Marco, Rao, Bhavya, Weir, Lynda, Evans, Alan, Matin, Rubeta, Harwood, Catherine, Szlosarek, Peter, Pickering, J Geoffrey, Fleming, Colin, Sim, Van Ren, Li, Su, Vasta, James T., Raines, Ronald T, Boniol, Mathieu, Thompson, Alastair, Proby, Charlotte, Crook, Tim, Syed, Nelofer
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Elsevier Science Ltd. 2020
Subjects:
Cell Biology
Biochemistry
Molecular Biology
Dermatology
Online Access:https://hdl.handle.net/1721.1/123511

Internet

https://hdl.handle.net/1721.1/123511

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