T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

In the small intestine, a niche of accessory cell types supports the generation of mature epithelial cell types from intestinal stem cells (ISCs). It is unclear, however, if and how immune cells in the niche affect ISC fate or the balance between self-renewal and differentiation. Here, we use single...

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Bibliographic Details
Main Authors: Biton, Moshe, Haber, Adam L., Rogel, Noga, Burgin, Grace, Beyaz, Semir, Schnell, Alexandra, Ashenberg, Orr, Su, Chien-Wen, Smillie, Christopher, Shekhar, Karthik, Chen, Zuojia, Wu, Chuan, Ordovas-Montanes, Jose Manuel, Alvarez, David, Herbst, Rebecca H., Zhang, Mei, Tirosh, Itay, Dionne, Danielle, Nguyen, Lan T., Xifaras, Michael, Shalek, Alexander K, von Andrian, Ulrich H., Graham, Daniel B., Rozenblatt-Rosen, Orit, Shi, Hai Ning, Kuchroo, Vijay, Yilmaz, Omer, Regev, Aviv, Xavier, Ramnik Joseph
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Elsevier Science Ltd. 2020
Online Access:https://hdl.handle.net/1721.1/123653

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https://hdl.handle.net/1721.1/123653

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