Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection

Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection

Sustained viremia after acute HIV infection is associated with profound CD4⁺ T cell loss and exhaustion of HIV-specific CD8⁺ T cell responses. To determine the impact of combination antiretroviral therapy (cART) on these processes, we examined the evolution of immune responses in acutely infected in...

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Bibliographic Details
Main Authors: Ndhlovu, Zaza M., Kazer, Samuel Weisgurt, Nkosi, Thandeka, Ogunshola, Funsho, Muema, Daniel M., Anmole, Gursev, Swann, Shayda A., Moodley, Amber, Dong, Krista, Reddy, Tarylee, Brockman, Mark A., Shalek, Alexander K, Ndung’u, Thumbi, Walker, Bruce
Other Authors: Ragon Institute of MGH, MIT and Harvard
Format: Article
Language:English
Published: American Association for the Advancement of Science 2020
Online Access:https://hdl.handle.net/1721.1/123661

Internet

https://hdl.handle.net/1721.1/123661

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