A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases

Background: Genomic medicine has paved the way for identifying biomarkers and therapeutically actionable targets for complex diseases, but is complicated by the involvement of thousands of variably expressed genes across multiple cell types. Single-cell RNA-sequencing study (scRNA-seq) allows the ch...

Full description

Bibliographic Details
Main Authors: Gawel, Danuta R., Serra-Musach, Jordi, Lilja, Sandra, Aagesen, Jesper, Arenas, Alex, Asking, Bengt, Bengnér, Malin, Björkander, Janne, Biggs, Sophie, Ernerudh, Jan, Hjortswang, Henrik, Karlsson, Jan-Erik, Köpsen, Mattias, Lee, Eun Jung, Lentini, Antonio, Li, Xinxiu, Magnusson, Mattias, Martínez-Enguita, David, Matussek, Andreas, Nestor, Colm E., Schäfer, Samuel, Seifert, Oliver, Sonmez, Ceylan, Stjernman, Henrik, Tjärnberg, Andreas, Wu, Simon, Åkesson, Karin, Shalek, Alexander K, Stenmarker, Margaretha, Zhang, Huan, Gustafsson, Mika, Benson, Mikael
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Springer Science+Business Media 2020
Subjects:
Genetics(clinical)
Molecular Medicine
Genetics
Molecular Biology
Online Access:https://hdl.handle.net/1721.1/123667

Internet

https://hdl.handle.net/1721.1/123667

Similar Items