Nitric oxide induced S-nitrosation causes base excision repair imbalance

It is well established that inflammation leads to the creation of potent DNA damaging chemicals, including reactive oxygen and nitrogen species. Nitric oxide can react with glutathione to create S-nitrosoglutathione (GSNO), which can in turn lead to S-nitrosated proteins. Of particular interest is t...

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Bibliographic Details
Main Authors: Engelward, Bevin P., Parrish, Marcus Curtis, Chaim, Isaac Alexander, Nagel, Zachary D., Tannenbaum, Steven R, Samson, Leona D, Engelward, Bevin P
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/123812