Selective N-monomethylation of primary anilines with dimethyl carbonate in continuous flow

Selective N-monomethylation of primary anilines with dimethyl carbonate in continuous flow

Selective N-monomethylation of anilines has been achieved under continuous flow conditions using dimethyl carbonate as a green methylating agent in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene. Our methodology takes advantage of the expanded process windows available in the continuous flow reg...

Full description

Bibliographic Details
Main Authors: Seo, Hyowon, Bedard, Anne Catherine, Chen, Willie P., Hicklin II, Robert William, Alabugin, Alexander, Jamison, Timothy F.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/123997

Internet

https://hdl.handle.net/1721.1/123997

Similar Items