Automated sequence design of 2D wireframe DNA origami with honeycomb edges

Wireframe DNA origami has emerged as a powerful approach to fabricating nearly arbitrary 2D and 3D geometries at the nanometer-scale. Complex scaffold and staple routing needed to design wireframe DNA origami objects, however, render fully automated, geometry-based sequence design approaches essenti...

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Bibliographic Details
Main Authors: Jun, Hyungmin, Wang, Xiao, Bricker, William P, Bathe, Mark
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer 2020
Online Access:https://hdl.handle.net/1721.1/124022