Enantioselective Allylation Using Allene, a Petroleum Cracking Byproduct

Allene (C₃H₄) gas is produced and separated on million-metric-ton scale per year during petroleum refining but is rarely employed in organic synthesis. Meanwhile, the addition of an allyl group (C₃H₅) to ketones is among the most common and prototypical reactions in synthetic chemistry. Herein, we r...

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Bibliographic Details
Main Authors: Liu, Richard, Zhou, Yujing, Yang, Yang, Buchwald, Stephen Leffler
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: American Chemical Society (ACS) 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/124335