An ingestible self-orienting system for oral delivery of macromolecules

Biomacromolecules have transformed our capacity to effectively treat diseases; however, their rapid degradation and poor absorption in the gastrointestinal (GI) tract generally limit their administration to parenteral routes. An oral biologic delivery system must aid in both localization and permeat...

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Bibliographic Details
Main Authors: Abramson, Alex, Caffarel Salvador, Ester, Khang, Minsoo, Dellal, David, Silverstein, David, Gao, Yuan, Cleveland, Cody, Collins, Joy E, Tamang, Siddartha M, Hayward, Alison M, Roxhed, Niclas, Langer, Robert S, Traverso, Carlo Giovanni
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/124359