Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade
Immunotherapy using checkpoint-blocking antibodies against PD-1 has produced impressive results in a wide range of cancers. However, the response remains heterogeneous among patients. We used noninvasive immuno-positron emission tomography (PET), using 89Zr-labeled PEGylated single-domain antibody f...
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Format: | Article |
Language: | English |
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Proceedings of the National Academy of Sciences
2020
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Online Access: | https://hdl.handle.net/1721.1/124404 |