Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens
Queuosine (Q) is a complex tRNA modification widespread in eukaryotes and bacteria that contributes to the efficiency and accuracy of protein synthesis. Eukaryotes are not capable of Q synthesis and rely on salvage of the queuine base (q) as a Q precursor. While many bacteria are capable of Q de nov...
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Format: | Article |
Language: | English |
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Proceedings of the National Academy of Sciences
2020
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Online Access: | https://hdl.handle.net/1721.1/124461 |