Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling

Early assessment of adverse drug effects in humans is critical to avoid long-lasting harm. However, current approaches for early detection of adverse effects still lack predictive and organ-specific biomarkers to evaluate undesired responses in humans. Microphysiological systems (MPSs) are in vitro...

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Bibliographic Details
Main Authors: Mina, Sara G., Alaybeyoglu, Begum, Murphy, William L., Thomson, James A., Stokes, Cynthia L., Cirit, Murat
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Frontiers Media SA 2020
Online Access:https://hdl.handle.net/1721.1/124482