Gain-of-function mutation of microRNA-140 in human skeletal dysplasia
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression. Heterozygous loss-of-function point mutations of miRNA genes are associated with several human congenital disorders 1–5 , but neomorphic (gain-of-new-function) mutations in miRNAs due to nucleotide substitutions have not been...
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| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media LLC
2020
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| Online Access: | https://hdl.handle.net/1721.1/124510 |