Increased PHGDH expression promotes aberrant melanin accumulation
Background: Copy number gain of the D-3-phosphoglycerate dehydrogenase (PHGDH) gene, which encodes the first enzyme in serine biosynthesis, is found in some human cancers including a subset of melanomas. Methods: In order to study the effect of increased PHGDH expression in tissues in vivo, we gener...
| Päätekijät: | , , , , |
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| Muut tekijät: | |
| Aineistotyyppi: | Artikkeli |
| Kieli: | English |
| Julkaistu: |
Springer Science and Business Media LLC
2020
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| Aiheet: | |
| Linkit: | https://hdl.handle.net/1721.1/124524 |