Enantiomeric glycosylated cationic block co-beta-peptides eradicate Staphylococcus aureus biofilms and antibiotic-tolerant persisters

The treatment of bacterial infections is hindered by the presence of biofilms and metabolically inactive persisters. Here, we report the synthesis of an enantiomeric block co-beta-peptide, poly(amido-D-glucose)-block-poly(beta-L-lysine), with high yield and purity by one-shot one-pot anionic-ring op...

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Bibliographic Details
Main Authors: Hammond, Paula T., Bazan, Guillermo C.
Other Authors: Singapore-MIT Alliance in Research and Technology (SMART)
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/124558