ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry

A heritable polymorphism within regulatory sequences of the LMO1 gene is associated with its elevated expression and increased susceptibility to develop neuroblastoma, but the oncogenic pathways downstream of the LMO1 transcriptional co-regulatory protein are unknown. Our ChIP-seq and RNA-seq analys...

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书目详细资料
Main Authors: Durbin, Adam D., Abraham, Brian J., Lawton, Lee N., Young, Richard A., Sanda, Takaomi
其他作者: Whitehead Institute for Biomedical Research
格式: 文件
语言:English
出版: Springer Science and Business Media LLC 2020
主题:
在线阅读:https://hdl.handle.net/1721.1/124654