ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry
A heritable polymorphism within regulatory sequences of the LMO1 gene is associated with its elevated expression and increased susceptibility to develop neuroblastoma, but the oncogenic pathways downstream of the LMO1 transcriptional co-regulatory protein are unknown. Our ChIP-seq and RNA-seq analys...
Main Authors: | Durbin, Adam D., Abraham, Brian J., Lawton, Lee N., Young, Richard A., Sanda, Takaomi |
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Other Authors: | Whitehead Institute for Biomedical Research |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/1721.1/124654 |
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