Impact of oncogenic pathways on evasion of antitumour immune responses

Immunotherapeutic interventions are showing effectiveness across a wide range of cancer types, but only a subset of patients shows clinical response to therapy. Responsiveness to checkpoint blockade immunotherapy is favoured by the presence of a local, CD8⁺ T cell-based immune response within the tu...

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Bibliographic Details
Main Author: Spranger, Stefani
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/124656