Basal constriction during midbrain–hindbrain boundary morphogenesis is mediated by Wnt5b and focal adhesion kinase

Basal constriction occurs at the zebrafish midbrain-hindbrain boundary constriction (MHBC) and is likely a widespread morphogenetic mechanism. 3D reconstruction demonstrates that MHBC cells are wedge-shaped, and initially constrict basally, with subsequent apical expansion. wnt5b is expressed in the...

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Bibliographic Details
Main Authors: Gutzman, Jennifer H., Graeden, Ellie, Brachmann, Isabel, Sive, Hazel
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:English
Published: The Company of Biologists 2020
Online Access:https://hdl.handle.net/1721.1/124660