Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance
Foxp3+ regulatory T (T reg) cells are pivotal regulators of immune tolerance, with T cell receptor (TCR)-driven activated T reg (aT reg) cells playing a central role; yet how TCR signaling propagates to control aT reg cell responses remains poorly understood. Here we show that TCR signaling induces...
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Rockefeller University Press
2020
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/1721.1/124683 |