The biosynthetic origin of psychoactive kavalactones in kava

Kava (Piper methysticum) is an ethnomedicinal shrub native to the Polynesian islands with well-established anxiolytic and analgesic properties. Its main psychoactive principles, kavalactones, form a unique class of polyketides that interact with the human central nervous system through mechanisms di...

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Bibliographic Details
Main Authors: Pluskal, Tomáš, Torrens-Spence, Michael P., Fallon, Timothy R., De Abreu, Andrea, Shi, Cindy H., Weng, Jing-Ke
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/124692