NUFIP1 is a ribosome receptor for starvation-induced ribophagy

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

The lysosome degrades and recycles macromolecules, signals to the master growth regulator mTORC1 [mechanistic target of rapamycin (mTOR) complex 1], and is associated with human disease.We performed quantitative proteomic analyses of rapidly isolated lysosomes and found that nutrient levels and mTOR...

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Bibliographic Details
Main Authors: Wyant, Gregory A., Abu-Remaileh, Monther, Frenkel, Evgeni M., Laqtom, Nouf N., Dharamdasani, Vimisha, Lewis, Caroline A., Chan, Sze Ham, Sabatini, David M.
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2020
Subjects:
Multidisciplinary
Online Access:https://hdl.handle.net/1721.1/124713

Internet

https://hdl.handle.net/1721.1/124713

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