NUFIP1 is a ribosome receptor for starvation-induced ribophagy
The lysosome degrades and recycles macromolecules, signals to the master growth regulator mTORC1 [mechanistic target of rapamycin (mTOR) complex 1], and is associated with human disease.We performed quantitative proteomic analyses of rapidly isolated lysosomes and found that nutrient levels and mTOR...
Main Authors: | Wyant, Gregory A., Abu-Remaileh, Monther, Frenkel, Evgeni M., Laqtom, Nouf N., Dharamdasani, Vimisha, Lewis, Caroline A., Chan, Sze Ham, Sabatini, David M. |
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Other Authors: | Whitehead Institute for Biomedical Research |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/1721.1/124713 |
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