Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques

Broadly neutralizing monoclonal antibodies protect against infection with HIV-1 in animal models, suggesting that a vaccine that elicits these antibodies would be protective in humans. However, it has not yet been possible to induce adequate serological responses by vaccination. Here, to activate B...

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Bibliographic Details
Main Author: Irvine, Darrell J.
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/124756