Enzyme Pretreatment plus Locally Delivered HB-IGF-1 Stimulate Integrative Cartilage Repair In Vitro

Focal cartilage defects caused by joint injury have a limited capacity to self-repair and, if left untreated, can lead to the early onset of osteoarthritis. The current standard of care, microfracture surgery, induces an endogenous repair response, but typically results in poorly integrated fibrocar...

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Bibliographic Details
Main Authors: Liebesny, Paul H., Mroszczyk, Keri, Zlotnick, Hannah, Hung, Han-Hwa, Frank, Eliot, Grodzinsky, Alan J.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Mary Ann Liebert Inc 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/124763