TGF-β signaling in cellular senescence and aging-related pathology

Aging is broadly defined as the functional decline that occurs in all body systems. The accumulation of senescent cells is considered a hallmark of aging and thought to contribute to the aging pathologies. Transforming growth factor-β (TGF-β) is a pleiotropic cytokine that regulates a myriad of cell...

Full description

Bibliographic Details
Main Authors: Tominaga, Kana, Suzuki, Hiroshi I.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: MDPI AG 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/124915