Altered exocrine function can drive adipose wasting in early pancreatic cancer

Changes in cell and organismal metabolism accompany malignancy1,2. Pancreatic ductal adenocarcinoma (PDAC) is associated with peripheral tissue wasting, a metabolic syndrome that lowers quality of life and is proposed to decrease cancer patient survival3,4. Tissue wasting is a multifactorial disease...

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Bibliographic Details
Main Authors: Danai, Laura V., Dennstedt, Emily A., Muir, Alexander, Lien, Evan C., Mayers, Jared R., Lau, Allison N., Jones-Sali, Paul, Vander Heiden, Matthew G.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/124925