Altered exocrine function can drive adipose wasting in early pancreatic cancer
Changes in cell and organismal metabolism accompany malignancy1,2. Pancreatic ductal adenocarcinoma (PDAC) is associated with peripheral tissue wasting, a metabolic syndrome that lowers quality of life and is proposed to decrease cancer patient survival3,4. Tissue wasting is a multifactorial disease...
Main Authors: | Danai, Laura V., Dennstedt, Emily A., Muir, Alexander, Lien, Evan C., Mayers, Jared R., Lau, Allison N., Jones-Sali, Paul, Vander Heiden, Matthew G. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2020
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Subjects: | |
Online Access: | https://hdl.handle.net/1721.1/124925 |
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