Structural and dynamic basis of substrate permissiveness in hydroxycinnamoyltransferase (HCT)

Substrate permissiveness has long been regarded as the raw materials for the evolution of new enzymatic functions. In land plants, hydroxycinnamoyltransferase (HCT) is an essential enzyme of the phenylpropanoid metabolism. Although essential enzymes are normally associated with high substrate specif...

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Bibliographic Details
Main Authors: Levsh, Olesya, Weng, Jing-Ke
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/124937