Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

Single-nucleus RNA-seq (snRNA-seq) enables the interrogation of cellular states in complex tissues that are challenging to dissociate or are frozen, and opens the way to human genetics studies, clinical trials, and precise cell atlases of large organs. However, such applications are currently limite...

Full description

Bibliographic Details
Main Author: Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/125028