Rapid CLIP dissociation from MHC II promotes an unusual antigen presentation pathway in autoimmunity
A number of autoimmunity-associated MHC class II proteins interact only weakly with the invariant chain-derived class II-associated invariant chain peptide (CLIP). CLIP dissociates rapidly from I-Ag7 even in the absence of DM, and this property is related to the type 1 diabetes-associated β57 polymo...
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| Format: | Article |
| Language: | English |
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Rockefeller University Press
2020
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| Online Access: | https://hdl.handle.net/1721.1/125033 |