Emerging Evidence of Chromosome Folding by Loop Extrusion

Emerging Evidence of Chromosome Folding by Loop Extrusion

Chromosome organization poses a remarkable physical problem with many biological consequences: How can molecular interactions between proteins at the nanometer scale organize micron-long chromatinized DNA molecules, insulating or facilitating interactions between specific genomic elements? The mecha...

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Bibliographic Details
Main Authors: Fudenberg, Geoffrey, Abdennur, Nezar Alexander, Imakaev, Maxim, Goloborodko, Anton, Mirny, Leonid A.
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory 2020
Online Access:https://hdl.handle.net/1721.1/125044

Internet

https://hdl.handle.net/1721.1/125044

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