MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo

MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo

Mitochondria are metabolic organelles that are essential for mammalian life, but the dynamics of mitochondrial metabolism within mammalian tissues in vivo remains incompletely understood. While whole-tissue metabolite profiling has been useful for studying metabolism in vivo, such an approach lacks...

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Bibliographic Details
Main Authors: Bayraktar, Erol C., Baudrier, Lou, Özerdem, Ceren, Lewis, Caroline A., Chan, Sze Ham, Kunchok, Tenzin, Abu-Remaileh, Monther, Cangelosi, Andrew L., Sabatini, David M., Birsoy, Kıvanç, Chen, Walter W.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: National Academy of Sciences 2020
Online Access:https://hdl.handle.net/1721.1/125078

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https://hdl.handle.net/1721.1/125078

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