Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing

The introduction of foreign DNA into cells and organisms has facilitated much of modern biological research, and it promises to become equally important in clinical practice. Locating sites of foreign DNA incorporation in mammalian genomes has proven burdensome, so the genomic location of most trans...

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Автори: Nicholls, Peter K., Bellott, Daniel W., Cho, Ting-Jan, Pyntikova, Tatyana, Page, David C.
Інші автори: Whitehead Institute for Biomedical Research
Формат: Стаття
Мова:English
Опубліковано: Genetics Society of America 2020
Онлайн доступ:https://hdl.handle.net/1721.1/125096