Chromosome segregation errors generate a diverse spectrum of simple and complex genomic rearrangements
Cancer genomes are frequently characterized by numerical and structural chromosomal abnormalities. Here we integrated a centromere-specific inactivation approach with selection for a conditionally essential gene, a strategy termed CEN-SELECT, to systematically interrogate the structural landscape of...
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Format: | Article |
Language: | English |
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Springer Science and Business Media LLC
2020
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Online Access: | https://hdl.handle.net/1721.1/125106 |