Implications of human genetic variation in CRISPR-based therapeutic genome editing
CRISPR-Cas genome-editing methods hold immense potential as therapeutic tools to fix disease-causing mutations at the level of DNA. In contrast to typical drug development strategies aimed at targets that are highly conserved among individual patients, treatment at the genomic level must contend wit...
| Main Authors: | , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2020
|
| Online Access: | https://hdl.handle.net/1721.1/125156 |