Production of Protein-Complex Components Is Stoichiometric and Lacks General Feedback Regulation in Eukaryotes

Constituents of multiprotein complexes are required at well-defined levels relative to each other. However, it remains unknown whether eukaryotic cells typically produce precise amounts of subunits, or instead rely on degradation to mitigate imprecise production. Here, we quantified the production r...

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Bibliographic Details
Main Authors: Taggart, James C., Li, Gene-Wei
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/125168