Optogenetic induction of the schizophrenia-related endophenotype of ventral hippocampal hyperactivity causes rodent correlates of positive and cognitive symptoms

Pathological over-activity of the CA1 subfield of the human anterior hippocampus has been identified as a potential predictive marker for transition from a prodromal state to overt schizophrenia. Psychosis, in turn, is associated with elevated activity in the anterior subiculum, the hippocampal outp...

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Bibliographic Details
Main Authors: Wolff, Amy R., Bygrave, Alexei M., Sanderson, David J., Boyden, Edward, Bannerman, David M., Kullmann, Dimitri M., Kaetzel, Dennis
Other Authors: McGovern Institute for Brain Research at MIT
Format: Article
Language:English
Published: Springer Nature 2020
Online Access:https://hdl.handle.net/1721.1/125242