Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice

Development of targeted cancer therapy requires a thorough understanding of mechanisms of tumorigenesis as well as mechanisms of action of therapeutics. This is challenging because by the time patients are diagnosed with cancer, early events of tumorigenesis have already taken place. Similarly, deve...

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Bibliographic Details
Main Authors: Kaur, Mandeep, Drake, Adam, Hu, Guangan, Rudnick, Stephen, Chen, Qingfeng, Phennicie, Ryan T., Attar, Ricardo, Nemeth, Jeffrey, Gaudet, Francois, Chen, Jianzhu
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: American Association of Immunologists 2020
Online Access:https://hdl.handle.net/1721.1/125268