Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture

Much of our understanding of chromosome segregation is based on cell culture systems. Here, we examine the importance of the tissue environment for chromosome segregation by comparing chromosome segregation fidelity across several primary cell types in native and nonnative contexts. We discover that...

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Những tác giả chính: Knouse, Kristin Ann, Bachofner, Marc, Amon, Angelika B, Lopez-Bernal, Kristina Elizabeth, 1980-
Tác giả khác: Koch Institute for Integrative Cancer Research at MIT
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Elsevier BV 2020
Truy cập trực tuyến:https://hdl.handle.net/1721.1/125270