Automated Sequence Design of 3D Polyhedral Wireframe DNA Origami with Honeycomb Edges

3D polyhedral wireframe DNA nanoparticles (DNA-NPs) fabricated using scaffolded DNA origami offer complete and independent control over NP size, structure, and asymmetric functionalization on the 10-100 nm scale. However, the complex DNA sequence design needed for the synthesis of these versatile DN...

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Bibliographic Details
Main Authors: Jun, Hyungmin, Shepherd, Tyson R, Zhang, Kaiming, Bricker, William P, Bathe, Mark
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Chemical Society (ACS) 2020
Online Access:https://hdl.handle.net/1721.1/125281