Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors

Cellular processes are carried out by many genes, and their study and optimization requires multiple levers by which they can be independently controlled. The most common method is via a genetically encoded sensor that responds to a small molecule. However, these sensors are often suboptimal, exhibi...

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Bibliographic Details
Main Authors: Meyer, Adam J., Segall-Shapiro, Thomas Hale, Glassey, Emerson, Zhang, Jing, Voigt, Christopher A.
Other Authors: Massachusetts Institute of Technology. Synthetic Biology Center
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/125283