Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

Adipocytes possess remarkable adaptive capacity to respond to nutrient excess, fasting or cold exposure, and they are thus an important cell type for the maintenance of proper metabolic health. Although the endoplasmic reticulum (ER) is a critical organelle for cellular homeostasis, the mechanisms t...

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Bibliographic Details
Main Authors: Bartelt, Alexander, Widenmaier, Scott B., Schlein, Christian, Johann, Kornelia, Goncalves, Renata L. S., Eguchi, Kosei, Fischer, Alexander W., Parlakgul, Gunes, Snyder, Nicole A., Nguyen, Truc B., Bruns, Oliver Thomas, Franke, Daniel, Bawendi, Moungi G, Lynes, Matthew D., Leiria, Luiz O., Tseng, Yu-Hua, Inouye, Karen E., Arruda, Ana Paula, Hotamisligil, Gokhan S.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Springer Nature 2020
Online Access:https://hdl.handle.net/1721.1/125337

Internet

https://hdl.handle.net/1721.1/125337

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