CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data

CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data

Tiling screens that use CRISPR-Cas technologies provide a powerful approach for the mapping of regulatory elements to phenotypes of interest1–6. Here we present CRISPR screening uncharacterized region function (CRISPR-SURF), a deconvolution framework that can be used to identify functional regulator...

Full description

Bibliographic Details
Main Authors: Hsu, Jonathan Y., Fulco, Charles P., Farouni, Rick, Clement, Kendell, Engreitz, Jesse Michael, Lander, Eric Steven, Pinello, Luca
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/125387

Internet

https://hdl.handle.net/1721.1/125387

Similar Items