Inhibition of tyrosine-phosphorylated STAT3 in human breast and lung cancer cells by Manuka honey is mediated by selective antagonism of the IL-6 receptor

Inhibition of tyrosine-phosphorylated STAT3 in human breast and lung cancer cells by Manuka honey is mediated by selective antagonism of the IL-6 receptor

Aberrantly high levels of tyrosine-phosphorylated signal transducer and activator of transcription 3 (p-STAT3) are found constitutively in ~50% of human lung and breast cancers, acting as an oncogenic transcription factor. We previously demonstrated that Manuka honey (MH) inhibits p-STAT3 in breast...

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Bibliographic Details
Main Authors: Aryappalli, Priyanka, Shabbiri, Khadija, Masad, Razan J., Al-Marri, Roadha H., Haneefa, Shoja M., Mohamed, Yassir A., Arafat, Kholoud, Attoub, Samir, Cabral-Marques, Otavio, Ramadi, Khalil, Fernandez-Cabezudo, Maria J., al-Ramadi, Basel K.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2020
Online Access:https://hdl.handle.net/1721.1/125388

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https://hdl.handle.net/1721.1/125388

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