A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells

Microfluidic-based organ-on-a-chip assays with simultaneous coculture of multi-cell types have been widely utilized for basic research and drug development. Here we describe a novel method for a primary cell-based corneal microphysiological system which aims to recapitulate the basic functions of th...

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Bibliographic Details
Main Authors: Bai, Jing, Fu, Haojie, Bazinet, Lauren, Birsner, Amy E., D'Amato, Robert J.
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: Frontiers Media SA 2020
Online Access:https://hdl.handle.net/1721.1/125467